Temiverine hydrochloride

CAS No. 136529-33-4

Temiverine hydrochloride( —— )

Catalog No. M33143 CAS No. 136529-33-4

Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 445 Get Quote
5MG 686 Get Quote
10MG 938 Get Quote
25MG 1398 Get Quote
50MG 1822 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Temiverine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.
  • Description
    Temiverine hydrochloride is a synthesized agent that is expected to have anticholinergic action. Temiverine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    Atropine (1 nM to 1 μM), Oxybutynin (10 nM to 10 μM), Temiverine (10 nM to 10 μM), and RCC-36 (10 nM to 1 μM) cause a parallel shift to the right of the concentration-response curves to acetylcholine stimulation.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    136529-33-4
  • Formula Weight
    422
  • Molecular Formula
    C24H36ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.O=C(OC(C#CCN(CC)CC)(C)C)C(O)(C=1C=CC=CC1)C2CCCCC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kikukawa H, et al.Pharmacologic actions of temiverine (p-INN) and its active metabolite, RCC-36, on isolated human urinary bladder muscle. Int J Urol. 1998 May;5(3):268-75.?
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